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KMID : 0032220200320060519
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Annals of Dermatology
2020 Volume.32 No. 6 p.519 ~ p.522
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Late Onset Foreign Body Reaction due to Poly-L-Lactic Acid Facial Injections for Cosmetic Purpose
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Jeon Yu-Jin
Koo Dae-Won
Lee Joong-Sun
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Abstract
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The safety and efficacy of Poly-L-lactic acid (PLLA) as an injectable facial volumizer for the treatment of lipoatrophy and facial rejuvenation has been widely proven. We experienced a remarkable case of deep-seated nodules on both the cheeks of 57-year-old female 18-months after administration of PLLA filler injection for cosmetic purpose and performed a skin biopsy. With hematoxylin and eosin stain, the nodule showed non-caseating granulomas consisting of histiocytes with central foreign bodies in the dermis. This case report represents the late-onset foreign body reaction due to PLLA facial injections.
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KEYWORD
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Foreign-body reaction, Granuloma, Poly-L-lactic acid
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